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Brainstem dysfunctions in Rett syndrome

Non-epileptic vacant spells

Concurrent electroencephalogram (EEG) and brainstem autonomic monitoring is at present the only clinical means of diagnosing non-epileptic behaviours in Rett syndrome, thereby saving some Rett patients from unnecessary administration of anti-epileptic drugs. We are able to identify "non-epileptic vacant spells", usually associated with involuntary movements and dystonic postures, which can be mistaken for clinical epileptic seizures. Rett patients with Valsalva's type of breathing, apneustic breathers and feeble breathers are all predisposed to non-epileptic vacant spells.


The graph and videos were recorded using the NeuroScopeT system
Click here to see the graph of Non-Epileptic vacant spells

Click here to see the video of Non-Epileptic vacant spells.

:: Brainstem Shutdown

:: Brainstem Epilepsy

:: Non-epileptic vacant spells

Julu, P.O.O (2001). The central autonomic disturbance in Rett syndrome. In: Kerr, A. and Witt Engerstrom, I (eds) Rett Disorder and the Developing Brain. Oxford University Press, Oxford, pp132-181.
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